Recombinant DPPA5 protein (His tag)

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Recombinant Human Developmental Pluripotency-Associated 5 Protein (hDPPA5) Fragment (1-116) is a high-purity, functional protein designed for studying pluripotency maintenance in embryonic stem cells. This fragment fully encompasses the KH and atypical domains, making it an ideal tool for domain-specific functional assays and molecular interaction studies.

The full-length Developmental Pluripotency-Associated 5 protein (also known as Embryonal Stem Cell-Specific Gene 1 protein) plays a critical role in maintaining embryonic stem cell pluripotency. According to functional annotations, hDPPA5 is involved in the maintenance of ES cell pluripotency, though it is dispensable for self-renewal of pluripotent ES cells and establishment of germ cells. The protein associates with specific target mRNAs, suggesting its involvement in post-transcriptional regulation. hDPPA5 is localized in the cytoplasm, where it likely performs its mRNA-binding functions. This recombinant fragment provides researchers with a targeted approach to investigate the specific molecular mechanisms underlying pluripotency regulation.