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  • Development regulating peptide Hym-331

Development regulating peptide Hym-331

Not For Human Use, Lab Use Only.

Cat.#: 319534

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Product Information

  • Product Name
    Development regulating peptide Hym-331
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    H-GPPPGLW-NH2
  • Sequence
    H-Gly-Pro-Pro-Pro-Gly-Leu-Trp-NH2
  • Length (aa)
    7
  • Peptide Purity (HPLC)
    95.44%
  • Molecular Formula
    C36H51N9O7
  • Molecular Weight
    721.84
  • Source
    Synthetic
  • Form
    Powder
  • Description

    The neuropeptide Hym-331, also known as Hydra-LWamide I, is a development-regulating peptide identified in the freshwater polyp Hydra magnipapillata. It is derived from a preprohormone containing multiple copies of immature neuropeptide sequences with a conserved C-terminal Gly-Leu-Trp-NH2 motif. The mature structure of Hym-331 is Gly-Pro-Pro-Pro-Gly-Leu-Trp-NH2, characterized by an N-terminal proline-rich region that may confer stability against enzymatic degradation.

    This peptide belongs to the LWamide family, which shares structural similarities with metamorphosis-inducing neuropeptides found in sea anemones. The processing of its precursor involves novel cleavage sites at serine and asparagine residues, indicating unique biosynthetic pathways in cnidarians. Based on its structural features and relationship to peptides involved in metamorphosis, Hym-331 is considered a candidate for regulating developmental processes in Hydra.

  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Leviev I, Williamson M, Grimmelikhuijzen CJ. Molecular cloning of a preprohormone from Hydra magnipapillata containing multiple copies of Hydra-L Wamide (Leu-Trp-NH2) neuropeptides: evidence for processing at Ser and Asn residues. J Neurochem. 1997;68(3):1319-25.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"