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Product Name
DEDD Polyclonal Antibody
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Description
Polyclonal antibody to DEDD
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Tested applications
WB, IHC
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Species reactivity
Human, Mouse, Rat
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Alternative names
DEDD antibody; CASP8IP1 antibody; DEDD1 antibody; DEFT antibody; FLDED1 antibody; KE05 antibody; death effector domain containing antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-318 of human DEDD (NP_001034801.1).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:2000
IHC 1:50 - 1:100 -
Validations
Immunohistochemistry - DEDD Polyclonal Antibody
Immunohistochemistry of paraffin-embedded rat lung using DEDD antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - DEDD Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human esophagus using DEDD antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - DEDD Polyclonal Antibody
Immunohistochemistry of paraffin-embedded mouse kidney using DEDD antibody at dilution of 1:100 (40x lens).
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Background
A scaffold protein that directs CASP3 to certain substrates and facilitates their ordered degradation during apoptosis. May also play a role in mediating CASP3 cleavage of KRT18. Regulates degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3. Inhibits DNA transcription in vitro (By similarity).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"