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  • Human CRTAM (His Tag) recombinant protein

Human CRTAM (His Tag) recombinant protein

Cat.#: 502064

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Product Information

  • Product Name
    Human CRTAM (His Tag) recombinant protein
  • Documents
  • Description
    Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo.
  • Protein name
    Cytotoxic and regulatory T-cell molecule
  • Protein short names
    CD355; CRTAM; MGC141606; MGC141607
  • Uniprot ID
    O95727
  • Gene Name
    CRTAM
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human CRTAM (NP_062550.2) extracellular domain (Met 1-Ser 286) was expressed, with a polyhistidine tag at the C-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human CRTAM consists of 280 amino acids and predictes a molecular mass of 31.4 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhCRTAM is approximately 50-60 kDa due to glycosylation.
  • Purity
    > 94 % as determined by SDS-PAGE
  • Activity
    Measured by its binding ability in a functional ELISA. Immobilized human CADM1 at 2 μg/ml (100 μl/well) can bind biotinylated human CRTAM with a linear range of 12.5-400 ng/ml.
  • Validations

    Human CRTAM Protein (His Tag) SDS-PAGE

    Human CRTAM Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"