Recombinant CTBP2 protein (His tag)

• DataSheet
• Material Safety Data Sheets (MSDS)

Recombinant Human C-terminal-binding protein 2 (CtBP2) fragment (residues 31-362) is a high-quality, stable protein designed for structural and biochemical studies. This 332-amino acid fragment, derived from the CTBP2 gene, represents a soluble and functional unit ideal for investigating CtBP2's role as a transcriptional corepressor and its involvement in cellular processes such as brown adipose tissue differentiation.

C-terminal-binding protein 2 (CtBP2), encoded by the CTBP2 gene in humans, functions as a corepressor that targets diverse transcription regulators. It plays a critical role in biological processes including brown adipose tissue differentiation. Additionally, specific isoforms, such as Isoform 2, are implicated in acting as scaffolds for specialized synapses. The protein is primarily localized to the nucleus, with synaptic presence highlighting its involvement in neural functions. This recombinant fragment (residues 31-362) was selected computationally to ensure stability and solubility, enabling reliable use in experimental applications without the complexities of the full-length protein.