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  • CRMP2 antibody
  • CRMP2 antibody
  • CRMP2 antibody
  • CRMP2 antibody
  • CRMP2 antibody

CRMP2 antibody

Cat.#: 109571

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Product Information

  • Product Name
    CRMP2 antibody
  • Documents
  • Description
    CRMP2 Rabbit Polyclonal antibody. Positive IHC detected in human testis tissue. Positive IF detected in SH-SY5Y cells. Positive WB detected in mouse brain tissue, SH-SY5Y cells. Positive IP detected in mouse brain tissue. Observed molecular weight by Western-blot: 62-66 kDa
  • Tested applications
    ELISA, WB, IHC, IP, IF
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    CRMP 2 antibody; CRMP2 antibody; DHPRP2 antibody; dihydropyrimidinase like 2 antibody; DPYSL2 antibody; DRP 2 antibody; DRP2 antibody; N2A3 antibody; ULIP 2 antibody; ULIP2 antibody; Unc 33 like phosphoprotein 2 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of CRMP2 recombinant protein (Accession Number: BC056408). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IP: 1:200-1:1000

    IHC: 1:20-1:200

    IF: 1:20-1:200

  • Validations

    mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:109571(DPYSL2 antibody) at dilution of 1:500

    mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:109571(DPYSL2 antibody) at dilution of 1:500

    Immunohistochemical of paraffin-embedded human testis using Catalog No:109571(DPYSL2 antibody) at dilution of 1:100 (under 10x lens)

    Immunohistochemical of paraffin-embedded human testis using Catalog No:109571(DPYSL2 antibody) at dilution of 1:100 (under 10x lens)

    Immunohistochemical of paraffin-embedded human testis using Catalog No:109571(DPYSL2 antibody) at dilution of 1:100 (under 40x lens)

    Immunohistochemical of paraffin-embedded human testis using Catalog No:109571(DPYSL2 antibody) at dilution of 1:100 (under 40x lens)

    IP Result of anti-DPYSL2 (IP:Catalog No:109571, 4ug; Detection:Catalog No:109571 1:300) with mouse brain tissue lysate 3200ug.

    IP Result of anti-DPYSL2 (IP:Catalog No:109571, 4ug; Detection:Catalog No:109571 1:300) with mouse brain tissue lysate 3200ug.

    Immunofluorescent analysis of SH-SY5Y cells using Catalog No:109571(DPYSL2 Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

    Immunofluorescent analysis of SH-SY5Y cells using Catalog No:109571(DPYSL2 Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

  • Background
    Dihydropyrimidinase-like 2 (Dpysl2), a protein involved in neuronal differentiation and axonal guidance is found altered in various nervous system diseases (PMID:19524114). It is also named as CRMP2, ULIP2 and belongs to hydantoinase/dihydropyrimidinase subfamily. The phosphorylation of the particular portion carboxyl-terminal to the basic region of DPYSL2 may play an important role in regulating its activity, and may be involved in the formation of degenerating neurites in AD brain(PMID:10757975).
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"