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Product Name
CRMP2 antibody
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Description
CRMP2 Rabbit Polyclonal antibody. Positive IHC detected in human testis tissue. Positive IF detected in SH-SY5Y cells. Positive WB detected in mouse brain tissue, SH-SY5Y cells. Positive IP detected in mouse brain tissue. Observed molecular weight by Western-blot: 62-66 kDa
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Tested applications
ELISA, WB, IHC, IP, IF
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
CRMP 2 antibody; CRMP2 antibody; DHPRP2 antibody; dihydropyrimidinase like 2 antibody; DPYSL2 antibody; DRP 2 antibody; DRP2 antibody; N2A3 antibody; ULIP 2 antibody; ULIP2 antibody; Unc 33 like phosphoprotein 2 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of CRMP2 recombinant protein (Accession Number: NM_001386). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:200-1:1000
IHC: 1:20-1:200
IF: 1:20-1:200
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Validations
mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:109571(DPYSL2 antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human testis using Catalog No:109571(DPYSL2 antibody) at dilution of 1:100 (under 10x lens)
Immunohistochemical of paraffin-embedded human testis using Catalog No:109571(DPYSL2 antibody) at dilution of 1:100 (under 40x lens)
IP Result of anti-DPYSL2 (IP:Catalog No:109571, 4ug; Detection:Catalog No:109571 1:300) with mouse brain tissue lysate 3200ug.
Immunofluorescent analysis of SH-SY5Y cells using Catalog No:109571(DPYSL2 Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Background
Dihydropyrimidinase-like 2 (Dpysl2), a protein involved in neuronal differentiation and axonal guidance is found altered in various nervous system diseases (PMID:19524114). It is also named as CRMP2, ULIP2 and belongs to hydantoinase/dihydropyrimidinase subfamily. The phosphorylation of the particular portion carboxyl-terminal to the basic region of DPYSL2 may play an important role in regulating its activity, and may be involved in the formation of degenerating neurites in AD brain(PMID:10757975).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"