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Product Name
Recombinant CORO protein (His tag)
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Description
Recombinant Coronin-like protein cor-1 (residues 1-396) from Caenorhabditis elegans, featuring a stable and soluble fragment ideal for investigating neuroblast migration mechanisms and cytoskeletal function in developmental biology research.
The full-length Coronin-like protein cor-1 is essential for directing the anterior migration of Q neuroblasts during larval development in C. elegans, with its function dependent on asymmetric expression within these cells. This protein localizes to the cytoplasm and cytoskeleton, where it plays a critical role in cellular migration processes fundamental to nervous system development. The provided fragment (residues 1-396) represents a computationally optimized stable domain, preserving key functional characteristics for structural and biochemical studies.
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Protein name
Coronin-like protein cor-1
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Uniprot ID
Q21624
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Gene Name
cor-1
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 1-396 aa (Q21624) were fused with 6His tag.
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Protein Species
Caenorhabditis elegans
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Molecular weight
Predictes a molecular mass of 45.95 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 47 kDa band.
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Purity
>88%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"