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Product Name
Recombinant COQ9 protein (His tag)
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Description
Recombinant Ubiquinone biosynthesis protein COQ9, mitochondrial (COQ9) fragment (residues 92-318) from Homo sapiens. This stable and soluble fragment is ideal for structural and biochemical studies, enabling researchers to explore its role in coenzyme Q biosynthesis and membrane interaction mechanisms.
Ubiquinone biosynthesis protein COQ9, mitochondrial, is a membrane-associated protein essential for coenzyme Q (ubiquinone) biosynthesis, a critical lipid-soluble electron transporter in aerobic cellular respiration. COQ9 specifically binds and presents aromatic isoprenes, such as ubiquinone intermediates, to COQ7, facilitating the hydroxylase step in the pathway. It localizes to the mitochondrion, where it associates with cardiolipin-rich membranes, deforming the lipid bilayer to access and interact with membrane-bound lipids, underscoring its importance in energy metabolism and mitochondrial function.
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Protein name
Ubiquinone biosynthesis protein COQ9, mitochondrial
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Uniprot ID
O75208
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Gene Name
COQ9; C16orf49
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 92-318 aa (O75208) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 27.33 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 28 kDa band.
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Purity
>90%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"