Complement factor B antibody

Cat.#: 109446

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Product Information

  • Product Name
    Complement factor B antibody
  • Documents
  • Description
    Complement factor B Rabbit Polyclonal antibody. Positive IHC detected in human liver tissue. Positive WB detected in human serum tissue, human blood tissue. Observed molecular weight by Western-blot: 93-100 kDa, 60-69 kDa
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human; other species not tested.
  • Alternative names
    BFD antibody; C3/C5 convertase antibody; CFAB antibody; CFB antibody; Complement factor B antibody; FBI12 antibody; GBG antibody; Glycine rich beta glycoprotein antibody; H2 Bf antibody; PBF2 antibody; Properdin factor B antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of Complement factor B recombinant protein (Accession Number: NM_001710). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IHC: 1:20-1:200

  • Validations

    human serum tissue were subjected to SDS PAGE followed by western blot with Catalog No:109446(CFB antibody) at dilution of 1:800

    human serum tissue were subjected to SDS PAGE followed by western blot with Catalog No:109446(CFB antibody) at dilution of 1:800

    Immunohistochemistry of paraffin-embedded human liver tissue slide using Catalog No:109446(CFB Antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemistry of paraffin-embedded human liver tissue slide using Catalog No:109446(CFB Antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemistry of paraffin-embedded human liver tissue slide using Catalog No:109446(CFB Antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemistry of paraffin-embedded human liver tissue slide using Catalog No:109446(CFB Antibody) at dilution of 1:50 (under 40x lens)

  • Background
    Complement factor B (CFB) is a component of the alternative pathway of complement activation. Complement factor B is cleaved into Ba and Bb by factor D in the presence of C3b. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"