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Recombinant COCH protein (His tag)

Recombinant COCH protein (His tag)

Cat.#: 546478

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Product Information

  • Product Name
    Recombinant COCH protein (His tag)
  • Documents
  • Description

    Recombinant Human Cochlin (COCH-5B2) Fragment (159-550) is a high-purity protein designed for studying the specific functions of the VWFA 1 and VWFA 2 domains. This 392-amino acid fragment serves as an essential tool for researchers investigating cell shape regulation and motility in contexts such as trabecular meshwork biology.

    Cochlin, encoded by the COCH gene, plays a critical role in controlling cell shape and motility within the trabecular meshwork, contributing to essential cellular dynamics. As a secreted protein localized to the extracellular space and extracellular matrix, it functions within the extracellular environment to mediate structural and motility-related processes. The provided fragment encompasses the key VWFA domains, enabling targeted investigation into their contributions to Cochlin's regulatory functions.

  • Protein name
    Cochlin
  • Uniprot ID
    O43405
  • Gene Name
    COCH; COCH5B2
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    DNA encoding 159-550 aa (O43405) were fused with 6His tag.
  • Sequence 
    159-550
  • Protein Species
    Human
  • Molecular weight
    Predictes a molecular mass of 44.84 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 45 kDa band.
  • Purity
    >89%, by SDS-PAGE with Coomassie Brilliant Blue staining.
  • Activity
    Not tested.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"