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Recombinant CHIT1 protein (His tag)

Recombinant CHIT1 protein (His tag)

Cat.#: 547257

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Special Price 294.7 USD

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Product Information

  • Product Name
    Recombinant CHIT1 protein (His tag)
  • Documents
  • Description

    Recombinant Human Chitotriosidase-1 (CHIT1) Fragment (aa 22-466) is a high-purity protein designed for studying chitinase activity and pathogen defense mechanisms. This fragment fully encompasses the GH18 catalytic and chitin-binding type-2 domains, making it an ideal tool for functional assays and biochemical research.

    Chitotriosidase-1 (EC 3.2.1.14) is a human chitinase that degrades chitin, chitotriose, and chitobiose, playing a key role in defense against nematodes and other pathogens. The protein is primarily secreted, with a minor lysosomal localization, indicating its involvement in extracellular immune responses while maintaining some intracellular storage. Research links its activity to protective mechanisms against chitin-containing pathogens, highlighting its relevance in immunology and infectious disease studies.

  • Protein name
    Chitotriosidase-1
  • Uniprot ID
    Q13231
  • Gene Name
    CHIT1
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    DNA encoding 22-466 aa (Q13231) were fused with 6His tag.
  • Protein Species
    Human
  • Molecular weight
    Predictes a molecular mass of 51.04 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 51 kDa band.
  • Purity
    >88%, by SDS-PAGE with Coomassie Brilliant Blue staining.
  • Activity
    Not tested.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"