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Product Name
CFHR1 Polyclonal Antibody
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Description
Polyclonal antibody to CFHR1
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Tested applications
WB
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Species reactivity
Human, Mouse, Rat
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Alternative names
CFHR1 antibody; CFHL antibody; CFHL1 antibody; CFHL1P antibody; CFHR1P antibody; FHR1 antibody; H36-1 antibody; H36-2 antibody; HFL1 antibody; HFL2 antibody; complement factor H related 1 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 151-330 of human CFHR1 (NP_002104.2).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:2000
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Validations
Western blot - CFHR1 Polyclonal Antibody
Western blot analysis of extracts of various cell lines, using CFHR1 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 30s.
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Background
Involved in complement regulation. The dimerized forms have avidity for tissue-bound complement fragments and efficiently compete with the physiological complement inhibitor CFH. Can associate with lipoproteins and may play a role in lipid metabolism.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"