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Product Name
Recombinant CES2 protein (His tag)
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Description
Our recombinant ces-2 protein fragment (residues 102-180) from Caenorhabditis elegans provides researchers with a specialized tool for studying the bZIP DNA-binding domain of this critical transcription factor involved in programmed cell death regulation and neuronal development.
Transcription factor ces-2 (Cell death specification protein 2) is a nuclear protein essential for activating programmed cell death in specific neuronal sister cells. It functions by binding to the DNA sequence 5'-RTTACGTAAY-3' and negatively regulating ces-1 activity, which in turn controls cell-killing genes. Beyond its apoptotic role, ces-2 collaborates with NFIL3 transcription factor homolog atf-2 to positively modulate embryonic transcription of lin-48 during excretory duct cell development and regulates expression of neuropeptide pigment dispersing factor homologs pdf-1 and pdf-2. The provided fragment encompasses the complete bZIP domain (residues 116-179), enabling focused investigation of this key functional region.
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Protein name
Transcription factor ces-2
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Uniprot ID
Q94126
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Gene Name
ces-2
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 102-180 aa (Q94126) were fused with 6His tag.
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Protein Species
Caenorhabditis elegans
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Molecular weight
Predictes a molecular mass of 10.94 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 11 kDa band.
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Purity
>87%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"