Cecropin 2 peptide

Cecropin 2 peptide

• Handling and Storage of Synthetic Peptides
• Material Safety Data Sheets (MSDS)

Batch to batch variation of the purity

GWLKKIGKKIERVGQHTRDATIQTIGVAQQAANVAATLK

Gly-Trp-Leu-Lys-Lys-Ile-Gly-Lys-Lys-Ile-Glu-Arg-Val-Gly-Gln-His-Thr-Arg-Asp-Ala-Thr-Ile-Gln-Thr-Ile-Gly-Val-Ala-Gln-Gln-Ala-Ala-Asn-Val-Ala-Ala-Thr-Leu-Lys

39

96%

Synthetic

Powder

Found in multiple species. The same peptide was also found in housefly (Liang Y et al. 2006 Dev Comp Immunol 30: 249-57). It has been recombinantly expressed in different manners. Mdc can interact with LPS, permeate membranes, and subsequently bind to DNA (Lu X et al. 2012 Appl Microbiol Biotechnol DOI 10.1007/s00253-011-3793-2). Updated 1/2012. Cecropin 2 has Antibacterial activity. Cecropin 2 was found in the Medfly, Ceratitis capitata; also housefly, Musca domestica.

Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides

• Rosetto M, Manetti AG, Marchini D, Dallai R, Telford JL, Baldari CT. Sequences of two cDNA clones from the medfly Ceratitis capitata encoding antibacterial peptides of the cecropin family. Gene. 1993;134(2):241-3.

Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.