CCL28 antibody

Cat.#: 109004

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Product Information

  • Product Name
    CCL28 antibody
  • Documents
  • Description
    CCL28 Rabbit Polyclonal antibody. Positive IHC detected in human colon tissue, human colon cancer tissue. Positive WB detected in human spleen tissue, Jurkat cells, PC-3 cells. Observed molecular weight by Western-blot: 8kd-9kd
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human, Mouse; other species not tested.
  • Alternative names
    C C motif chemokine 28 antibody; CCK1 antibody; CCL28 antibody; MEC antibody; Protein CCK1 antibody; SCYA28 antibody; Small inducible cytokine A28 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of CCL28 recombinant protein (Accession Number: NM_001301874). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IHC: 1:20-1:200

  • Validations

    human spleen tissue were subjected to SDS PAGE followed by western blot with Catalog No:109004(CCL28 antibody) at dilution of 1:300

    human spleen tissue were subjected to SDS PAGE followed by western blot with Catalog No:109004(CCL28 antibody) at dilution of 1:300

    Immunohistochemical of paraffin-embedded human colon using Catalog No:109004(CCL28 antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemical of paraffin-embedded human colon using Catalog No:109004(CCL28 antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemical of paraffin-embedded human colon using Catalog No:109004(CCL28 antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemical of paraffin-embedded human colon using Catalog No:109004(CCL28 antibody) at dilution of 1:50 (under 40x lens)

  • Background
    CCL28, also named as SCYA28, CCK1 and MEC, belongs to the intercrine beta (chemokine CC) family. It has chemotactic activity for resting CD4, CD8 T-cells and eosinophils. CCL28 binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner. CCL28 is expressed in a variety of human and mouse tissues, and it appears to be predominantly produced by epithelial cells. It is produced by epithelial cells of these tissues suggesting that this chemokine can play an important role by linking homing mechanisms between the gut, nasal mucosa and mammary gland (MG). In WB test, CCL28 is 14kd and 8-9kd(a putatively to a degradation fragment).

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"