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Product Name
CCL25 Polyclonal Antibody
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Description
Polyclonal antibody to CCL25
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Tested applications
WB, IHC, IF
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Species reactivity
Human
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Alternative names
CCL25 antibody; Ckb15 antibody; SCYA25 antibody; TECK antibody; C-C motif chemokine 25 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 24-150 of human CCL25 (NP_005615.2).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:2000
IHC 1:100 - 1:200
IF 1:50 - 1:100 -
Validations
Immunohistochemistry - CCL25 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human liver using CCL25 antibody at dilution of 1:100 (40x lens).
Immunofluorescence - CCL25 Polyclonal Antibody
Immunofluorescence analysis of HeLa cells using CCL25 antibody . Blue: DAPI for nuclear staining.
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Background
Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Isoform 2 is an antagonist of isoform 1. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"