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Product Name
CCL22 Polyclonal Antibody
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Description
Polyclonal antibody to CCL22
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Tested applications
IHC
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Species reactivity
Human, Rat
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Alternative names
CCL22 antibody; A-152E5.1 antibody; ABCD-1 antibody; DC/B-CK antibody; MDC antibody; SCYA22 antibody; STCP-1 antibody; C-C motif chemokine 22 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-93 of human CCL22 (NP_002981.2).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
IHC 1:50 - 1:100
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Validations
Immunohistochemistry - CCL22 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded rat kidney using CCL22 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - CCL22 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human colon using CCL22 antibody at dilution of 1:100 (40x lens).
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Background
May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes, dendritic cells and natural killer cells. Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4. Processed forms MDC(3-69), MDC(5-69) and MDC(7-69) seem not be active.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"