CBS Polyclonal Antibody

Cat.#: 162007

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Product Information

  • Product Name
    CBS Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to CBS
  • Tested applications
    WB, IF
  • Species reactivity
    Human, Mouse
  • Alternative names
    CBS antibody; HIP4 antibody; cystathionine beta-synthase antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 252-551 of human CBS (NP_000062.1).
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:2000
    IF 1:50 - 1:200
  • Validations

    Western blot - CBS Polyclonal Antibody

    Western blot - CBS Polyclonal Antibody

    Western blot analysis of extracts of various cell lines, using CBS antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.

    Immunofluorescence - CBS Polyclonal Antibody

    Immunofluorescence - CBS Polyclonal Antibody

    Immunofluorescence analysis of U2OS cells using CBS antibody . Blue: DAPI for nuclear staining.

  • Background
    Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine. Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons (By similarity).

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"