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  • αs1-casein-derived peptide 1

αs1-casein-derived peptide 1

Not For Human Use, Lab Use Only.

Cat.#: 300597

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* Buy 1 get 1 free (?) What is TFA?

Special Price 227.70 USD

Availability: 1-2 weeks
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Product Information

  • Product Name
    αs1-casein-derived peptide 1
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    H-RYLGY-OH
  • Sequence
    H-Arg-Tyr-Leu-Gly-Tyr-OH
  • Length (aa)
    18
  • Peptide Purity (HPLC)
    95.93%
  • Molecular Formula
    C32H46N8O8
  • Molecular Weight
    670.75
  • Source
    Synthetic
  • Form
    Powder
  • Description
    The source of αs1-casein-derived peptide 1 is bovine (Bos taurus).
    αs1-casein-derived peptide 1 is one of the α s1-casein-derived peptides and has been shown to have antihypertensive activity and interact with opioid receptors.
    The peptide αs1-casein-derived peptide 1 is resistant to gastrointestinal enzymes and can survive intact until the distal part of the small intestine.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Stuknytė M, Cattaneo S, Masotti F, De Noni I. Occurrence and fate of ACE-inhibitor peptides in cheeses and in their digestates following in vitro static gastrointestinal digestion. Food Chem. 2015 Feb 1;168:27-33.
    • Basiricò L, Catalani E, Morera P, Cattaneo S, Stuknytė M, Bernabucci U, De Noni I, Nardone A. Release of angiotensin converting enzyme-inhibitor peptides during in vitro gastrointestinal digestion of Parmigiano Reggiano PDO cheese and their absorption through an in vitro model of intestinal epithelium. J Dairy Sci. 2015 Nov;98(11):7595-601.
    • Sánchez-Rivera L, Ferreira Santos P, Sevilla MA, Montero MJ, Recio I, Miralles B. Implication of Opioid Receptors in the Antihypertensive Effect of a Bovine Casein Hydrolysate and αs1-Casein-Derived Peptides. J Agric Food Chem. 2020 Feb 19;68(7):1877-1883.
    • Morais ATDB, Morais STB, Feitor JF, Santos WG, Gomes da Silva Catunda L, Walkling-Ribeiro M, Ahrne L, Cardoso DR. Impact of Physicochemical Modifications in Casein Promoted by UV-C on the Peptide Profile of Gastric Digestion and the Transepithelial Transport of Peptides. J Agric Food Chem. 2023 May 17;71(19):7495-7507.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"