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Product Name
Human Carbonic Anhydrase II (His Tag) recombinant protein
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Description
Essential for bone resorption and osteoclast differentiation (By similarity). Reversible hydration of carbon dioxide. Can hydrate cyanamide to urea. Involved in the regulation of fluid secretion into the anterior chamber of the eye. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6.
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Protein name
Carbonic anhydrase 2
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Protein short names
CARBONIC ANHYDRASE II; CAII; LTW-5; CAR-2; LVTW-5; CAR2; CA2; CA-II; AI131712
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Uniprot ID
V9HW21
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Gene Name
CA2
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human CA2 (NP_000058.1) (Met 1-Lys 260) was expressed, with a polyhistide tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human CA2 consisting of 266 amino acids and has a calculated molecular mass of 30 kDa as estimated in SDS-PAGE under reducing conditions.
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Purity
> 96 % as determined by SDS-PAGE
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Activity
Measured by its esterase activity. The specific activity is >150 pmoles/min/μg.
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Validations
Human Carbonic Anhydrase II / CA2 Protein (His Tag) SDS-PAGE
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