CACNA1E Polyclonal Antibody

Cat.#: 160346

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Product Information

  • Product Name
    CACNA1E Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to CACNA1E
  • Tested applications
    WB
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    CACNA1E antibody; BII antibody; CACH6 antibody; CACNL1A6 antibody; Cav2.3 antibody; gm139 antibody; calcium voltage-gated channel subunit alpha1 E antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 2014-2313 of human CACNA1E (NP_001192222.1).
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:2000
  • Validations

    Western blot - CACNA1E Polyclonal Antibody

    Western blot - CACNA1E Polyclonal Antibody

    Western blot analysis of extracts of various cell lines, using CACNA1E antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 30s.

  • Background
    Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. R-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by nickel. They are however insensitive to dihydropyridines (DHP). Calcium channels containing alpha-1E subunit could be involved in the modulation of firing patterns of neurons which is important for information processing.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"