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Product Name
Human CCL23 / MIP 3 recombinant protein
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Description
Shows chemotactic activity for monocytes, resting T-lymphocytes, and neutrophils, but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are more potent chemoattractants than the small-inducible cytokine A23.
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Protein name
C-C motif chemokine 23
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Protein short names
MEMBER 23; SCYA23; SMALL INDUCIBLE CYTOKINE SUBFAMILY A (CYS-CYS); SMALL-INDUCIBLE CYTOKINE A23; C-C MOTIF CHEMOKINE 23; MYELOID PROGENITOR INHIBITORY FACTOR 1; CKB8; MIP3; MIP-3; CHEMOKINE (C-C MOTIF) LIGAND 23; CCL23; MPIF-1; HMRP-2A; MACROPHAGE INFLAMMATORY PROTEIN 3; CKB-8-1; C6 BETA-CHEMOKINE; CK-BETA-8; CKB-8
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Uniprot ID
P55773
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Gene Name
CCL23; MIP3; MPIF1; SCYA23
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human CCL23 (AAB51134.1) (Arg22-Asn120) was expressed.
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Protein Species
Human
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Molecular weight
The recombinant human CCL23 consists of 99 amino acids and predicts a molecular mass of 11.4 KDa. It migrates as an approximately 18 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Human CCL23 / MIP 3 Protein SDS-PAGE
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