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Product Name
Recombinant BTNL8 protein (His tag)
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Description
Recombinant Butyrophilin-like protein 8 (BTNL8) fragment (amino acids 18-238) is a high-quality protein tool designed for immunological research. This fragment fully encompasses the Ig-like V-type domains, enabling focused studies on their role in T-cell stimulation and immune response modulation.
Butyrophilin-like protein 8 (BTNL8) is a human single-pass type I membrane protein localized to the cell membrane. It functions as an immunomodulatory protein that stimulates primary immune responses by acting on T-cells sub-optimally stimulated through the TCR/CD3 complex, promoting their proliferation and cytokine production. This recombinant fragment preserves the key functional Ig-like V-type domains, making it valuable for investigating domain-specific mechanisms in immune regulation.
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Protein name
Butyrophilin-like protein 8
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Uniprot ID
Q6UX41
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Gene Name
BTNL8
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 18-238 aa (Q6UX41) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 26.55 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 27 kDa band.
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Purity
>86%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"