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  • BTN3A1 antibody

BTN3A1 antibody

Cat.#: 108547

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Product Information

  • Product Name
    BTN3A1 antibody
  • Documents
  • Description
    BTN3A1 Rabbit Polyclonal antibody. Positive WB detected in U-937 cells, Jurkat cells. Observed molecular weight by Western-blot: 48 kDa
  • Tested applications
    ELISA, WB
  • Species reactivity
    Human; other species not tested.
  • Alternative names
    BT3.1 antibody; BTF5 antibody; BTN3A1 antibody; CD277 antibody
  • Immunogen
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of BTN3A1 recombinant protein (Accession Number: BC121800). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

  • Validations

    U-937 cells were subjected to SDS PAGE followed by western blot with Catalog No:108547(BTN3A1 Antibody) at dilution of 1:600

    U-937 cells were subjected to SDS PAGE followed by western blot with Catalog No:108547(BTN3A1 Antibody) at dilution of 1:600

  • Background
    BTN3A1, also named as Butyrophilin subfamily 3 member A1 or BTF5, is a 513 amino acid protein ,which contains one B30.2/SPRY domain and two Ig-like V-type (immunoglobulin-like) domains. BTN3A1 localizes in the cell membrane and belongs to the immunoglobulin superfamily. BTN/MOG family. BTN3A1 is detected on T-cells, natural killer cells, dendritic cells and macrophages. It is ubiquitously highly expressed in heart, pancreas and lung and moderately expressed in placenta, liver and muscle. BTN3A1 plays a role in T-cell activation and in the adaptive immune response. It also regulates the proliferation of activated T-cells and the release of cytokines and IFNG by activated T-cells. It exists as four isoforms. We detected a 48 kda isoform by western blot.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"