BTN3A1 Rabbit Polyclonal antibody. Positive WB detected in U-937 cells, Jurkat cells. Observed molecular weight by Western-blot: 48 kDa
Human; other species not tested.
BT3.1 antibody; BTF5 antibody; BTN3A1 antibody; CD277 antibody
This antibody was obtained by immunization of BTN3A1 recombinant protein (Accession Number: BC121800). Purification method: Antigen affinity purified.
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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U-937 cells were subjected to SDS PAGE followed by western blot with Catalog No:108547(BTN3A1 Antibody) at dilution of 1:600
BTN3A1, also named as Butyrophilin subfamily 3 member A1 or BTF5, is a 513 amino acid protein ,which contains one B30.2/SPRY domain and two Ig-like V-type (immunoglobulin-like) domains. BTN3A1 localizes in the cell membrane and belongs to the immunoglobulin superfamily. BTN/MOG family. BTN3A1 is detected on T-cells, natural killer cells, dendritic cells and macrophages. It is ubiquitously highly expressed in heart, pancreas and lung and moderately expressed in placenta, liver and muscle. BTN3A1 plays a role in T-cell activation and in the adaptive immune response. It also regulates the proliferation of activated T-cells and the release of cytokines and IFNG by activated T-cells. It exists as four isoforms. We detected a 48 kda isoform by western blot.
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