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Product Name
Recombinant BT3A1 protein (His tag)
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Description
Recombinant Human Butyrophilin subfamily 3 member A1 (CD277) Fragment (aa 30-254) is a high-purity protein encompassing the Ig-like V-type domains, optimized for studying T-cell activation and immune response mechanisms in research applications.
Butyrophilin subfamily 3 member A1 (BTN3A1), also known as CD277, is a key regulator of T-cell activation and adaptive immunity. It modulates T-cell proliferation and controls cytokine and IFNG release, particularly in response to infected or transformed cells with elevated phosphorylated metabolite levels. As a single-pass type I membrane protein localized to the cell membrane, BTN3A1 plays a critical role in immune surveillance and cellular defense mechanisms.
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Protein name
Butyrophilin subfamily 3 member A1
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Uniprot ID
O00481
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Gene Name
BTN3A1; BTF5
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 30-254 aa (O00481) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 25.81 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 26 kDa band.
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Purity
>90%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"