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Product Name
Recombinant BT1A1 protein (His tag)
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Description
Recombinant Human Butyrophilin subfamily 1 member A1 (BTN1A1) Fragment (aa 27-242) is a high-purity protein designed to encompass the Ig-like V-type 1 and Ig-like V-type 2 domains. This fragment serves as an essential tool for investigating BTN1A1's roles in milk-fat droplet secretion and T-cell proliferation inhibition, enabling targeted functional studies.
Butyrophilin subfamily 1 member A1 (BTN1A1) is a human membrane protein localized to the membrane and secreted forms. It functions in the secretion of milk-fat droplets, potentially acting as a membrane-associated receptor for cytoplasmic droplet association with the apical plasma membrane. Additionally, BTN1A1 inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, suppresses T-cell metabolism, and reduces secretion of IL2 and IFNG, highlighting its significance in immune regulation and lactation biology.
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Protein name
Butyrophilin subfamily 1 member A1
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Uniprot ID
Q13410
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Gene Name
BTN1A1; BTN
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 27-242 aa (Q13410) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 25.60 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 27 kDa band.
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Purity
>88%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"