BMPR2 antibody

Cat.#: 108469

Size:

Special Price 239.0 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    BMPR2 antibody
  • Documents
  • Description
    BMPR2 Rabbit Polyclonal antibody. Positive FC detected in PC-3 cells. Positive WB detected in human heart tissue, mouse brain tissue. Positive IP detected in mouse brain tissue. Observed molecular weight by Western-blot: 120 kDa
  • Tested applications
    ELISA, WB, IP, FC
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    BMP type 2 receptor antibody; BMP type II receptor antibody; BMPR 2 antibody; BMPR II antibody; BMPR2 antibody; BMPR3 antibody; BMR2 antibody; BRK 3 antibody; FLJ41585 antibody; FLJ76945 antibody; PPH1 antibody; T ALK antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of BMPR2 recombinant protein (Accession Number: NM_001204). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:1000-1:10000

    IP: 1:500-1:5000

  • Validations

    human heart tissue were subjected to SDS PAGE followed by western blot with Catalog No:117204(BMPR2 antibody) at dilution of 1:400

    human heart tissue were subjected to SDS PAGE followed by western blot with Catalog No:117204(BMPR2 antibody) at dilution of 1:400

    IP Result of anti-BMPR2 (IP:Catalog No:117204, 4ug; Detection:Catalog No:117204 1:1500) with mouse brain tissue lysate 4000ug.

    IP Result of anti-BMPR2 (IP:Catalog No:117204, 4ug; Detection:Catalog No:117204 1:1500) with mouse brain tissue lysate 4000ug.

    1X10^6 PC-3 cells were stained with 0.2ug BMPR2 antibody (Catalog No:117204, red) and control antibody (blue). Fixed with 4% PFA blocked with 3% BSA (30 min). Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) with dilution 1:1500.

    1X10^6 PC-3 cells were stained with 0.2ug BMPR2 antibody (Catalog No:117204, red) and control antibody (blue). Fixed with 4% PFA blocked with 3% BSA (30 min). Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) with dilution 1:1500.

  • Background
    BMPs (bone morphogenetic protein) are involved in endochondral bone formation and embryogenesis. BMPR2 encodes a member of the (BMP) receptor family of transmembrane serine/threonine kinases. It is a widely expressed receptor, with high mRNA expression during development in many tissues. Dimer of BMPR2 receptors (70-80 kD) forms a complex with a dimer of type I BMPR1(50-55 kD) in signal transduction. This antibody recognizes endogenous levels of total BMPR2 protein, including 115 kD precursor, 75 kD mature form and 150 kD dimer.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"