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Recombinant BLTP2 protein (His tag)

Cat.#: 538056

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Product Information

  • Product Name
    Recombinant BLTP2 protein (His tag)
  • Documents
  • Description

    Recombinant human Bridge-like lipid transfer protein family member 2 (BLTP2) fragment (residues 1750-2029) is a high-quality protein product designed for structural and biochemical studies. This 280-amino acid fragment, computationally selected for stability and solubility, enables researchers to investigate the lipid transport functions of BLTP2 in a manageable and functional format.

    Bridge-like lipid transfer protein family member 2 (BLTP2) is a tube-forming lipid transport protein that specifically binds to phosphatidylinositols and modulates the distribution of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2), playing a crucial role in cellular lipid homeostasis. The protein localizes to multiple membrane compartments, including the cell membrane, endoplasmic reticulum membrane, and mitochondrial membrane, where it facilitates lipid transfer at membrane contact sites such as endoplasmic reticulum-cell membrane and endoplasmic reticulum-mitochondria interfaces. This strategic localization underscores its importance in inter-organelle lipid trafficking and membrane dynamics.

  • Protein name
    Bridge-like lipid transfer protein family member 2
  • Uniprot ID
    Q14667
  • Gene Name
    BLTP2; BCOX1; KIAA0100
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    DNA encoding 1750-2029 aa (Q14667) were fused with N-terminal 6His tag.
  • Sequence 
    MNHKVHHHHH HGGSVDTFTL IHHELEISTN PAQYAMILDI VNNLLLHVEP KRKEHSEKKQ RVRFQLEISS NPEEQRSSIL
HLQEAVRQHV AQIRQLEKQM YSIMKSLQDD SKNENLLDLN QKLQLQLNQE KANLQLESEE LNILIRCFKD FQLQRANKME
LRKQQEDVSV VRRTEFYFAQ ARWRLTEEDG QLGIAELELQ RFLYSKVNKS DDTAEHLLEL GWFTMNNLLP NAVYKVVLRP
QSSCQSGRQL ALRLFSKVRP PVGGISVKEH FEVNVVPLTI QLTHQFFHRM MGFF
  • Protein Species
    Human
  • Molecular weight
    Predictes a molecular mass of 34.64 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 35 kDa band.
  • Purity
    >85%, by SDS-PAGE with Coomassie Brilliant Blue staining.
  • Activity
    Not tested.
  • Validations

    Recombinant BLTP2 protein (His tag) SDS-PAGE

    Recombinant BLTP2 protein (His tag) SDS-PAGE

    M: Marker; Lane 1: BLTP2; Lane 2: BSA

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"