Recombinant BGBP2 protein (His tag)

Recombinant BGBP2 protein (His tag)

Cat.#: 534660

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Product Information

  • Product Name
    Recombinant BGBP2 protein (His tag)
  • Documents
  • Description

    Recombinant Drosophila melanogaster Gram-negative bacteria-binding protein 2 (GNBP2) fragment (residues 21-461) is a high-purity protein designed for studying innate immune recognition. This 441-amino acid fragment contains the complete CBM39 and GH16 functional domains, making it an ideal tool for investigating beta-1,3-glucan binding and phenoloxidase cascade activation mechanisms.

    Gram-negative bacteria-binding protein 2 (GNBP2) from Drosophila melanogaster plays a critical role in innate immunity by recognizing invading microorganisms. The protein specifically binds to beta-1,3-glucan and activates the phenoloxidase cascade, an important defense mechanism against pathogens. According to its subcellular localization, GNBP2 is a secreted protein, allowing it to function in extracellular immune surveillance. The full-length protein's ability to detect microbial components makes it a key molecule in understanding pattern recognition receptor systems in invertebrate immunity.

  • Protein name
    Gram-negative bacteria-binding protein 2
  • Uniprot ID
    Q9VVR4
  • Gene Name
    GNBP2
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    DNA encoding 21-461 aa (Q9VVR4) were fused with 6His tag.
  • Protein Species
    Drosophila melanogaster
  • Molecular weight
    Predictes a molecular mass of 52.13 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 54 kDa band.
  • Purity
    >86%, by SDS-PAGE with Coomassie Brilliant Blue staining.
  • Activity
    Not tested.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"