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Product Name
Recombinant BAIP2 protein (His tag)
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Description
Recombinant Human BAIAP2 (1-250) fragment is a high-purity protein encompassing the IMD domain, essential for studying actin cytoskeleton regulation, membrane ruffling, and filopodia formation in cellular processes.
The full-length BAIAP2 protein, also known as IRSp53, functions as a crucial adapter protein that links membrane-bound small G-proteins like CDC42 and RAC1 to cytoplasmic effectors, facilitating actin cytoskeleton reorganization. It plays a key role in neurite growth, filopodia formation through synergy with ENAH, and response to bacterial infection by participating in actin bundling with EPS8. Located in the cytoplasm, membrane periphery, filopodia, and ruffles, BAIAP2 is recruited to actin pedestals during bacterial infections, highlighting its importance in cellular structure and pathogen response.
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Protein name
BAR/IMD domain-containing adapter protein 2
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Uniprot ID
Q9UQB8
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Gene Name
BAIAP2
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 1-250 aa (Q9UQB8) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 30.22 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 31 kDa band.
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Purity
>87%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"