Recombinant AT1B1 protein (His tag)

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This recombinant protein product features a stable and soluble fragment (residues 73-320) of Sodium/potassium-transporting ATPase subunit beta-1 from Caenorhabditis elegans. It is designed for structural and biochemical studies, offering researchers a reliable tool to investigate the regulatory functions of this essential ion transport component.

The full-length Sodium/potassium-transporting ATPase subunit beta-1 is a non-catalytic subunit of the sodium-potassium pump, which catalyzes ATP hydrolysis coupled with the exchange of sodium and potassium ions across the plasma membrane. It regulates the transport of sodium pumps to the plasma membrane through assembly with alpha subunits and may also function in the peptidic vesicle transport pathway from the endoplasmic reticulum, particularly in defecation behaviors. The protein is localized to the cell membrane as a single-pass type II membrane protein, underscoring its critical role in cellular ion homeostasis and membrane transport processes.