ARHGEF16 antibody

ARHGEF16 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

ARHGEF16 Rabbit Polyclonal antibody. Positive IHC detected in human pancreas cancer tissue. Positive WB detected in mouse kidney tissue. Observed molecular weight by Western-blot: 80 kDa

ELISA, IHC, WB

Human, Mouse; other species not tested.

ARHGEF16 antibody; GEF16 antibody; NBR antibody

Rabbit IgG

This antibody was obtained by immunization of ARHGEF16 recombinant protein (Accession Number: XM_024446454). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Small GTPases of the Rho family are critical regulators of various cellular functions including actin cytoskeleton organization, activation of kinase cascades, mitogenesis, transcriptional activation and stimulation of DNA synthesis. Rho proteins cycle between a biologically active GTP-bound state and an inactive GDP-bound state. Rho guanine nucleotide exchange factor (GEF) has a crucial role in activating small GTPase by exchange GDP for GTP. ARGEF16 is one of the multiple GEF members. Although the specific function of this protein is not known yet, it is thought to be involved in protein-protein and protein-lipid interactions.

• Lee J, Park B, Kim G. Arhgef16, a novel Elmo1 binding partner, promotes clearance of apoptotic cells via RhoG-dependent Rac1 activation. Biochimica et biophysica acta. 1843(11):2438-47. 2014.