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Product Name
Anti-YY1 Rabbit antibody
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Description
YY1 Rabbit polyclonal antibody
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Tested applications
WB, IHC-P, ICC/IF, IP
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Species reactivity
Human, Mouse, Rat
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthesized peptide derived from human YY1
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Clonality
Polyclonal
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Formulation
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/500-1/3000
IHC: 1/50-1/200
ICC/IF: 1/100-1/500
IP: 1/50-1/100
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Validations
Immunofluorescent analysis of Hela cells, using YY1 Antibody.
Immunohistochemical analysis of paraffin-embedded human bladder using YY1 Antibody.
Western blot analysis of YY1 expression in (1) HeLa cell lysate; (2) Daudi cell lysate.
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Background
Swiss-Prot Acc.P25490.Its activity is regulated by transcription factors and cytoplasmic proteins that have been shown to abrogate or completely inhibit YY1-mediated activation or repression. For example, it acts as a repressor in absence of adenovirus E1A protein but as an activator in its presence. Acts synergistically with the SMAD1 and SMAD4 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"