Anti-TXN antibody

Anti-TXN antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Rabbit Polyclonal to Mouse TXN

WB, ELISA, ICC/IF, IF

Mouse Thioredoxin/TXN/SASP

Thioredoxin antibody; ADF antibody; AW550880 antibody; MGC61975 antibody; RP11-427L11.1 antibody; RP23-332H16.1 antibody; Thioredoxin antibody; TRX antibody; Trx1 antibody; TRX1 antibody; TXN antibody; Txn antibody; Txn1 antibody; DKFZp686B1993 antibody

Rabbit IgG

Produced in rabbits immunized with purified, recombinant Mouse Thioredoxin/TXN/SASP . Thioredoxin/TXN/SASP specific IgG was purified by Mouse Thioredoxin/TXN/SASP affinity chromatography.

Polyclonal

0.2 μm filtered solution in PBS

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Thioredoxin, also known as ATL-derived factor, Surface-associated sulphydryl protein, SASP and TXN, is a nucleus, cytoplasm and secreted protein which belongs to the thioredoxin family. Thioredoxins are proteins that act as antioxidants by facilitating the reduction of other proteins by cysteine thiol-disulfide exchange. Thioredoxins are found in nearly all known organisms and are essential for life in mammals. Thioredoxin / TXN participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Thioredoxin / TXN plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Thioredoxin / TXN nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Thioredoxin / TXN induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.