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Product Name
Anti-Tuberin Rabbit antibody
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Description
Tuberin Rabbit monoclonal antibody
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Tested applications
WB, IHC-P, ICC/IF, FC, IP
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Species reactivity
Human
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Isotype
IgG
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Preparation
Antigen: A synthetic peptide of human Tuberin
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Clonality
Monoclonal
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Formulation
50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/5000
IHC: 1/20
ICC/IF: 1/20
FC: 1/200-1/1000
IP: 1/20
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Validations
Western blot detection of Tuberin in Hela,A549,MCF-7,293T cell lysates using Tuberin Rabbit mAb(1:1000 diluted).Predicted band size:201kDa.Observed band size:201kDa.
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Background
Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"