Anti-SELPLG antibody

Anti-SELPLG antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Rabbit Monoclonal to Mouse SELPLG

FCM

Mouse PSGL-1/CD162

CD162 antibody; CD162 antibody; CLA antibody; Psgl1 antibody; PSGL1 antibody; Psgl-1 antibody; PSGL-1 antibody; Selp1 antibody; Selpl antibody; SELPLG antibody; Selplg antibody; CLA antibody; CD162 antibody; PSGL1 antibody; PSGL-1 antibody; CD162 antibody; Psgl1 antibody; Selp1 antibody; Selpl antibody; Psgl-1 antibody

Rabbit IgG

This antibody was obtained from a rabbit immunized with purified, recombinant Mouse PSGL-1/CD162 .

Monoclonal

0.2 μm filtered solution in PBS

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

P-selectin glycoprotein ligand-1 (PSGL-1), also known as SELPLG or CD162, is the high affinitycounter-receptor for P-selectin on expressed on activated endothelial cells and platelets. PSGL-1 is a mucin-type glycoprotein, expressed on leukocytes and platelets as a homodimer of two disulfide-linked subunits of ~120 kD. As cell adhesion molecules, multiple studies have shown that PSGL-1/ P-selectin interaction is required for the normal recruitment of leukocytes during inflammatory reactions, and also participates in hemostatic responses. PSGL-1 protein requires two distinct posttranslational modifications for the Ca2+-dependent recognition by the lectin domain of P-selectin, that is tyrosine sulfation and specific O-linked glycosylation (sialic acid and fucose). PSGL-1 can also bind to other two members of the selectin family, E-selectin (endothelial) and L-selectin (leukocyte), but binds best to P-selectin.