Anti-SCN9A antibody

Cat.#: 175108

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Product Information

  • Product Name
    Anti-SCN9A antibody
  • Documents
  • Description
    Rabbit polyclonal antibody to SCN9A
  • Tested applications
    ICC, IHC-P, FC
  • Species reactivity
    Human
  • Alternative names
    PN1 antibody; ETHA antibody; NENA antibody; SFNP antibody; FEB3B antibody; NE-NA antibody; GEFSP7 antibody; HSAN2D antibody; Nav1.7 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antigen of this antibody was synthetic peptide within human nav1.7 aa 1-50 (cytoplasmic).
  • Clonality
    Polyclonal
  • Formulation
    Liquid, 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage instructions
    Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
  • Applications

    ICC: 1:50-1:200

    ICC: 1:50-1:200

    FC: 1:50-1:100

  • Validations

    Fig1: ICC staining NaV1.7 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

    Fig1: ICC staining NaV1.7 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

    Fig2: ICC staining NaV1.7 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

    Fig2: ICC staining NaV1.7 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

    Fig3: ICC staining NaV1.7 in SH-SY5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

    Fig3: ICC staining NaV1.7 in SH-SY5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

    Fig4: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-NaV1.7 beta antibody. Counter stained with hematoxylin.

    Fig4: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-NaV1.7 beta antibody. Counter stained with hematoxylin.

    Fig5: Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-NaV1.7 beta antibody. Counter stained with hematoxylin.

    Fig5: Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-NaV1.7 beta antibody. Counter stained with hematoxylin.

    Fig6: Flow cytometric analysis of SH-SY5Y cells with NaV1.7 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

    Fig6: Flow cytometric analysis of SH-SY5Y cells with NaV1.7 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

  • Background
  • References
    • Henningsen K et al. Candidate hippocampal biomarkers of susceptibility and resilience to stress in a rat model of depression. Mol Cell Proteomics 11:M111.016428 (2012).
    • Weiss J et al. Loss-of-function mutations in sodium channel Nav1.7 cause anosmia. Nature 472:186-90 (2011).

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"