Anti-phospho-MEK4/MKK4 (Ser80) Rabbit antibody

Cat.#: 167583

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Product Information

  • Product Name
    Anti-phospho-MEK4/MKK4 (Ser80) Rabbit antibody
  • Documents
  • Description
    phospho-MEK4/MKK4 (Ser80) Rabbit monoclonal antibody
  • Tested applications
    WB, IHC-P, IP
  • Species reactivity
    Human, Mouse
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic phosphopeptide corresponding to residues surrounding Ser80 of human MEK4/MKK4
  • Clonality
    Monoclonal
  • Formulation
    50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/2000

    IHC: 1/20

    IP: 1/20

  • Validations

    Western blot detection of phospho-MEK4/MKK4 (Ser80) in A549,MCF-7,U251 cell lysates using phospho-MEK4/MKK4 (Ser80) Rabbit mAb(1:1000 diluted).Predicted band size:44kDa.Observed band size:44kDa.

    Western blot detection of phospho-MEK4/MKK4 (Ser80) in A549,MCF-7,U251 cell lysates using phospho-MEK4/MKK4 (Ser80) Rabbit mAb(1:1000 diluted).Predicted band size:44kDa.Observed band size:44kDa.

  • Background
    This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"