Anti-Phospho-Glutamate Receptor 1 (AMPA subtype) (Ser845) Rabbit antibody

Anti-Phospho-Glutamate Receptor 1 (AMPA subtype) (Ser845) Rabbit antibody

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• Material Safety Data Sheets (MSDS)

Phospho-Glutamate Receptor 1 (AMPA subtype) (Ser845) Rabbit monoclonal antibody

WB

Human, Mouse, Rat

GLUH1; GLUR1; GLURA; GluA1; HBGR1 antibody

Rabbit IgG

Antigen: A synthetic phosphopeptide corresponding to residues surrounding Ser845 of human AMPA Receptor 1 (GluA1)

Monoclonal

Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.

Swiss-Prot Acc.P42261.Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.