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Product Name
Anti-Peroxiredoxin 2/PRP Rabbit antibody
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Description
Peroxiredoxin 2/PRP Rabbit polyclonal antibody
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Tested applications
WB, IHC-P, ICC/IF, FC
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Species reactivity
Human, Mouse, Rat
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Alternative names
PRP; TSA; PRX2; PTX1; TPX1; NKEFB; PRXII; TDPX1; NKEF-B; HEL-S-2a antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human Peroxiredoxin 2
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Clonality
Polyclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at -20°C. Stable for 12 months from date of receipt.
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Applications
WB: 1/1000-1/5000
IHC: 1/50-1/200
ICC/IF: 1/20-1/100
FC: 1/20-1/100
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Validations
Western blot detection of Peroxiredoxin 2/PRP in K562 cell lysates using Peroxiredoxin 2/PRP Rabbit pAb(1:1000 diluted).Predicted band size:22kDa.Observed band size:22kDa.
Immunohistochemistry of Peroxiredoxin 2 in paraffin-embedded Human breast cancer tissue using Peroxiredoxin 2 Rabbit pAb at dilution 1/50
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Background
Swiss-Prot Acc.P32119.Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"