Anti-p44/42 MAPK (ERK1/2) Rabbit antibody

Cat.#: 169076

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Product Information

  • Product Name
    Anti-p44/42 MAPK (ERK1/2) Rabbit antibody
  • Documents
  • Description
    p44/42 MAPK (ERK1/2) Rabbit polyclonal antibody
  • Tested applications
    WB, ICC/IF, IP, FC
  • Species reactivity
    Human, Mouse, Rat
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthesized peptide derived from human ERK1/2
  • Clonality
    Polyclonal
  • Formulation
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/500-1/2000

    ICC/IF: 1/50-1/200

    IP: 1/50

    FC: 1/200

  • Validations

    Immunofluorescent analysis of Hela cells, using ERK1/2 Antibody.

    Immunofluorescent analysis of Hela cells, using ERK1/2 Antibody.

    Western blot analysis of extracts from K562, Jurkat and Hela cells using p44/42 MAPK (ERK1/2) Rabbit pAb at 1:1000 dilution. Predicted band size: 42/44kDa. Observed band size: 42kDa.

    Western blot analysis of extracts from K562, Jurkat and Hela cells using p44/42 MAPK (ERK1/2) Rabbit pAb at 1:1000 dilution. Predicted band size: 42/44kDa. Observed band size: 42kDa.

    Western blot analysis of ERK1/2 Antibody expression in HepG2 whole cell lysates.

    Western blot analysis of ERK1/2 Antibody expression in HepG2 whole cell lysates.

  • Background
    Swiss-Prot Acc.P27361,P28482.ERK1 p42 MAP kinase plays a critical role in the regulation of cell growth and differentiation. Activated by a wide variety of extracellular signals including growth and neurotrophic factors, cytokines, hormones and neurotransmitters.ERK2 p44 MAP kinase plays a critical role in the regulation of cell growth and differentiation. Acts as an integration point for multiple biochemical signals, and is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"