-
Product Name
Anti-NRG1 antibody
- Documents
-
Description
Rabbit polyclonal to NRG1
-
Tested applications
ELISA, WB
-
Species reactivity
Human NRG1
-
Alternative names
HGL antibody; HGL antibody; 6030402G23Rik antibody; ARIA antibody; ARIA antibody; D230005F13Rik antibody; GGF antibody; GGF antibody; GGF2 antibody; GGFII antibody; Hgl antibody; HRG antibody; HRG antibody; HRG1 antibody; HRGA antibody; HRGalpha antibody; MST131 antibody; NDF antibody; NDF antibody; SMDF antibody; SMDF antibody; GGF antibody; HRG antibody; NDF antibody; ARIA antibody; GGF2 antibody; HRG1 antibody; HRGA antibody; SMDF antibody; MST131 antibody; MSTP131 antibody; NRG1-IT2 antibody; GGF antibody; HRG antibody; Hgl antibody; NDF antibody; ARIA antibody; SMDF antibody; GGFII antibody; HRGalpha antibody; 6030402G23Rik antibody; D230005F13Rik antibody
- Immunogen
-
Isotype
Rabbit IgG
-
Preparation
Produced in rabbits immunized with purified, recombinant Human NRG1 (rh NRG1; Q02297-1; Ser20-Lys241). NRG1 specific IgG was purified by Human NRG1 affinity chromatography.
-
Clonality
Polyclonal
-
Formulation
0.2 μm filtered solution in PBS
-
Storage instructions
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. -
Applications
WB: 5-10 μg/ml
ELISA: 0.1-0.2 μg/ml
This antibody can be used at 0.1-0.2 μg/ml with the appropriate secondary reagents to detect Human NRG1.
-
Validations
NRG1 Antibody, Rabbit PAb, Antigen Affinity Purified, Western blot
-
Background
Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The multiple isoforms perform diverse functions such as inducing growth and differentiation of epithelial, glial, neuronal, and skeletal muscle cells; inducing expression of acetylcholine receptor in synaptic vesicles during the formation of the neuromuscular junction; stimulating lobuloalveolar budding and milk production in the mammary gland and inducing differentiation of mammary tumor cells; stimulating Schwann cell proliferation; implication in the development of the myocardium such as trabeculation of the developing heart. Isoform 10 may play a role in motor and sensory neuron development.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"