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Product Name
Anti-non-muscle Myosin IIA Rabbit antibody
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Description
non-muscle Myosin IIA Rabbit monoclonal antibody
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Tested applications
WB, IHC-P, IP
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Species reactivity
Human, Mouse, Rat
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Isotype
IgG
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Preparation
Antigen: A synthetic peptide of human non-muscle Myosin IIA
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Clonality
Monoclonal
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Formulation
50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/1000
IHC: 1/50
IP: 1/20
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Validations
Western blot detection of non-muscle Myosin IIA in Hela,A549,HL-60,U2OS,C6 cell lysates using non-muscle Myosin IIA Rabbit mAb(1:1000 diluted).Predicted band size:227kDa.Observed band size:227kDa.
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Background
This gene encodes a conventional non-muscle myosin; this protein should not be confused with the unconventional myosin-9a or 9b (MYO9A or MYO9B). The encoded protein is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain which is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in this gene have been associated with non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness. [provided by RefSeq, Dec 2011]
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"