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Product Name
Anti-NAT1 Rabbit antibody
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Description
NAT1 Rabbit monoclonal antibody
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Tested applications
WB
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Species reactivity
Human
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Alternative names
AAC1; MNAT; NATI; NAT-1 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human NAT1
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Clonality
Monoclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/1000-1/5000
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Validations
Western blot detection of NAT1 in C6,3T3,Hela cell lysates using NAT1 Rabbit mAb(1:1000 diluted).Predicted band size:34kDa.Observed band size:34kDa.
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Background
Swiss-Prot Acc.P18440.Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens.MiscellaneousNAT1 was historically considered to be monomorphic in nature but reports of allelic variations at the NAT1 locus suggest that it is a polymorphically expressed enzyme.CautionThe allelic variation Ile-149 designated as NAT1*17 is part of the NAT1*11 allelic variation as reported by the nomenclature committee.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"