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Product Name
Anti-MYH7B antibody
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Description
Rabbit monoclonal antibody to MYH7B
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Tested applications
WB
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Species reactivity
Rat, Human, Mouse
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Alternative names
MHC14 antibody; MYH14 antibody
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Isotype
IgG
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Preparation
This antigen of this antibody was recombinant protein within c-terminal human myh7b.
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Clonality
Monoclonal
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Formulation
Liquid, 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage instructions
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
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Applications
WB:1:500-1:1,000
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Validations
Fig1:; Western blot analysis of MYH7B on different lysates. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. The primary antibody ( 1/500) was used in 5% BSA at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody (HA1001) at 1:5,000 dilution was used for 1 hour at room temperature.; Positive control:; Lane 1: rat skeletal muscle tissue lysate; Lane 2: rat heart tissue lysate
- Background
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References
- Peter AK. et. al. Expression of Normally Repressed Myosin Heavy Chain 7b in the Mammalian Heart Induces Dilated Cardiomyopathy. J Am Heart Assoc. 2019 Aug.
- Chen P. et. al. MYH7B variants cause hypertrophic cardiomyopathy by activating the CaMK-signaling pathway. Sci China Life Sci. 2020 Mar.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"