Anti-LRRK1 antibody

Cat.#: 176679

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Product Information

  • Product Name
    Anti-LRRK1 antibody
  • Documents
  • Description
    Mouse monoclonal antibody to LRRK1
  • Tested applications
    WB, IHC-P
  • Species reactivity
    Human, Mouse
  • Alternative names
    RIPK6 antibody; Roco1 antibody
  • Isotype
    IgG2b
  • Preparation
    This antigen of this antibody was peptide
  • Clonality
    Monoclonal
  • Formulation
    Liquid, 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage instructions
    Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
  • Applications

    WB: 1:500

    IHC-P: 1:50-1:100

  • Validations

    Fig1: Western blot analysis of LRRK1 on A549 lysate using anti-LRRK1 antibody at 1/100 dilution.

    Fig1: Western blot analysis of LRRK1 on A549 lysate using anti-LRRK1 antibody at 1/100 dilution.

    Fig2: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-LRRK1 antibody. Counter stained with hematoxylin.

    Fig2: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-LRRK1 antibody. Counter stained with hematoxylin.

    Fig3: Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-LRRK1 antibody. Counter stained with hematoxylin.

    Fig3: Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-LRRK1 antibody. Counter stained with hematoxylin.

    Fig4: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-LRRK1 antibody. Counter stained with hematoxylin.

    Fig4: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-LRRK1 antibody. Counter stained with hematoxylin.

  • Background
  • References
    • Guo L et al. Identification of a novel LRRK1 mutation in a family with osteosclerotic metaphyseal dysplasia.J Hum Genet 62(3):437-441 (2017).
    • Sejwal K et al. Cryo-EM analysis of homodimeric full-length LRRK2 and LRRK1 protein complexes.Sci Rep 7(1):8667 (2017).

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"