Anti-IL5RA antibody

Anti-IL5RA antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Rabbit Polyclonal to Mouse IL5RA

WB

Mouse IL5RA (CD125)

IL5R antibody; CD125 antibody; CDw125 antibody; HSIL5R3 antibody; Il5r antibody; CD125 antibody; CDw125 antibody; CDw125 antibody; CDw125 antibody; CD125 antibody; CD125 antibody; HSIL5R3 antibody; Il5r antibody; IL5R antibody; Il5ra antibody; IL5RA antibody; MGC26560 antibody

Rabbit IgG

Produced in rabbits immunized with purified, recombinant Mouse IL5RA (CD125). IL5RA (CD125) specific IgG was purified by Mouse IL5RA (CD125) affinity chromatography.

Polyclonal

0.2 μm filtered solution in PBS

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Interleukin 5 receptor, alpha (IL5RA) also known as CD125 (Cluster of Differentiation 125) is a subunit of the Interleukin-5 receptor. IL5RA (CD125) is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Six alternatively spliced transcript variants encoding three distinct isoforms have been reported. IL5RA (CD125) is a T-cell-derived cytokine which is particularly important in the development of asthma for the lerminal differentiation, activation and survival of committed cosinophil precursors.