Anti-IL-3 antibody

Anti-IL-3 antibody

• Material Safety Data Sheets (MSDS)

Rabbit polyclonal to IL-3

IHC-P

Mouse IL3

BPA antibody; PSF antibody; HCGF antibody; Il-3 antibody; MCGF antibody; Csfmu antibody; IL-3 antibody; MCGF antibody; MULTI-CSF antibody; Csfmu antibody; IL3 antibody; IL-3 antibody; MCGF antibody; MCGF antibody; MGC79398 antibody; PSF antibody; RP23-309E16.5 antibody; BPA antibody; HCGF antibody; Il3 antibody; IL-3 antibody; MGC79399 antibody; MULTI-CSF antibody

Rabbit IgG

Produced in rabbits immunized with A synthetic peptide corresponding to the N-terminus of the mouse IL3., and purified by antigen affinity chromatography.

Polyclonal

0.2 μm filtered solution in PBS

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

IL3 (interleukin 3), also known as IL-3, is a potent growth promoting cytokine which belongs to the IL-3 family. IL3/IL-3 also belongs to the group of interleukins. Interleukins are produced by a wide variety of body cells. The function of the immune system depends in a large part on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by helper CD4+ T lymphocytes, as well as through monocytes, macrophages, and endothelial cells. They promote the development and differentiation of T, B, and hematopoietic cells. IL3/IL-3 is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. IL3/IL-3 has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.

• Meyer CG, et al.. (2011) IL3 variant on chromosomal region 5q31-33 and protection from recurrent malaria attacks. Hum Mol Genet. 20(6):1173-81.
• Zambrano A, et al. (2010) IL-3 controls tau modifications and protects cortical neurons from neurodegeneration. Curr Alzheimer Res. 7(7):615-24.
• Dentelli P, et al.. (2011) IL-3 is a novel target to interfere with tumor vasculature. Oncogene. 30(50):4930-40.