Anti-IL-17F antibody

Cat.#: 101548

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Product Information

  • Product Name
    Anti-IL-17F antibody
  • Documents
  • Description
    Rabbit polyclonal to IL-17F
  • Tested applications
    ELISA, WB, IP
  • Species reactivity
    Human IL-17F
  • Alternative names
    Il17f antibody; IL17F antibody; IL-17F antibody; IL-17F antibody; ML1 antibody; ML-1 antibody; C87042 antibody; IL-24 antibody; interleukin 17F antibody; CANDF6 antibody; cytokine ML-1 antibody; interleukin-24 antibody; mutant IL-17F antibody; interleukin 17F antibody; ML1 antibody; ML-1 antibody; CANDF6 antibody; IL-17F antibody; C87042 antibody; IL-17F antibody
  • Immunogen
  • Isotype
    Rabbit IgG
  • Preparation
    Produced in rabbits immunized with purified, recombinant Human IL-17F (rh IL-17F; NP_443104.1; Arg31-Gln163). IL-17F specific IgG was purified by Human IL-17F affinity chromatography.
  • Clonality
    Polyclonal
  • Formulation
    0.2 μm filtered solution in PBS
  • Storage instructions
    This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
    Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
  • Applications

    WB: 1-10 μg/ml

    ELISA: 0.1-0.2 μg/mL

    This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human IL-17F.

    IP: 4-6 μg/mg of lysate

  • Validations

    IL-17F Antibody, Rabbit PAb, Antigen Affinity Purified, Western blot

    IL-17F Antibody, Rabbit PAb, Antigen Affinity Purified, Western blot

    IL-17F Antibody, Rabbit PAb, Antigen Affinity Purified, Immunoprecipitation

    IL-17F Antibody, Rabbit PAb, Antigen Affinity Purified, Immunoprecipitation

  • Background
    Ligand for IL17RA and IL17RC (PubMed:17911633). The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (PubMed:18684971). Involved in stimulating the production of other cytokines such as IL6, IL8 and CSF2, and in regulation of cartilage matrix turnover (PubMed:11591732, PubMed:11591768, PubMed:11574464). Also involved in stimulating the proliferation of peripheral blood mononuclear cells and T-cells and in inhibition of angiogenesis (PubMed:11591732). Plays a role in the induction of neutrophilia in the lungs and in the exacerbation of antigen-induced pulmonary allergic inflammation (By similarity).

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"