Anti-IGF2BP2 antibody

Cat.#: 141771

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Product Information

  • Product Name
    Anti-IGF2BP2 antibody
  • Documents
  • Description
    Rabbit Polyclonal to Human IGF2BP2
  • Tested applications
    IHC-P, ICC/IF, IF
  • Species reactivity
    Human IGF2BP2/IMP2
  • Alternative names
    RP23-50H13.1 antibody; IMP2 antibody; IMP-2 antibody; VICKZ2 antibody; Imp2 antibody; IMP-2 antibody; Neilsen antibody; C330012H03Rik antibody; C330012H03Rik antibody; IGF2BP2 antibody; Igf2bp2 antibody; IMP2 antibody; Imp2 antibody; IMP-2 antibody; IMP-2 antibody; Neilsen antibody; p62 antibody; VICKZ2 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Produced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the Human IGF2BP2/IMP2, and purified by antigen affinity chromatography.
  • Clonality
    Polyclonal
  • Formulation
    0.2 μm filtered solution in PBS
  • Storage instructions
    This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
    Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
  • Applications

    IHC-P: 0.1-2μg/mL

    ICC/IF: 0.5-3μg/mL

  • Validations

    Human IGF2BP2/IMP2 Immunofluorescence(IF) 15415

    Human IGF2BP2/IMP2 Immunofluorescence(IF) 15415

    Human IGF2BP2/IMP2 Immunohistochemistry(IHC) 15414

    Human IGF2BP2/IMP2 Immunohistochemistry(IHC) 15414

  • Background
    Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) is a member of the IGF-II mRNA-binding protein (IMP) family. IGF2BP2 is a member of a family of mRNA binding proteins that, collectively, have been shown to bind to several different mRNAs in mammalian cells, including one of the mRNAs encoding insulin-like growth factor-2. Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) is involved in the stimulation of insulin action. IGF2BP2 / IMP2 is expressed in oocytes, granulosa cells of small and growing follicles, Leydig cells, spermatogonia and semen (at protein level). It is also expressed in testicular cancer (at protein level). It is expressed weakly in heart, placenta, skeletal muscle, bone marrow, colon, kidney, salivary glands, testis and pancreas. IGF2BP2 binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. This binding is isoform-specific. IGF2BP2 may regulate translation of target mRNAs.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"